Requirement
Every administrator knows that allowing users to create their own personal sites in Mysites can easily become a problem if not managed properly. Thankfully, it is very easy to disable this feature in SharePoint 2010.

Solution

1. Open Central Administration -> Manage Service Applications -> User Profile Service
2. Click Manage User Permissions
3. Untick the box that corresponds to the ‘Create Personal Site’ permission.
4. 
5. Click on OK to save your changes.
6. Browse to Mysite, the ‘My Content’ link no longer appears.
7.